Release Date: November 1, 2021
Expiration Date: October 31, 2022

Target Audience
This activity is intended for community and academic medical oncologists, hematologic oncologists, advanced practitioners (NP/PA/PharmD), and other clinicians who treat patients with lymphoma and myeloma.

Learning Objectives
Upon completion of this activity learners should be able to:

•  Incorporate CAR T-cell therapy into their clinical practice, and identify appropriate patients
•  Develop strategies to mitigate treatment-related adverse events that may occur during treatment with CAR T-cell therapy
•  Discuss the emerging results of clinical trials that are investigating CAR T-cell therapies in lymphoma and myeloma
•  Optimize the referral process and multidisciplinary care for patients who qualify for CAR T-cell therapy

Continuing Education

In support of improving patient care, this activity has been planned and implemented by University of Nebraska Medical Center and Bio Ascend.  University of Nebraska Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Nebraska Medical Center designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Method of Participation
There are no fees for participating in and receiving CME credit for this activity. During the accredited period, participants must:

1) read the educational objectives and conflict of interest disclosures; 2) study the educational activity; 3) complete the pre- and post-test and evaluation.

Participants who complete the educational activity, pre- and post-test, and evaluation will receive a certificate of credit.

Faculty and Planning Committee Disclosures

As a jointly accredited provider, the University of Nebraska Medical Center (UNMC) ensures accuracy, balance, objectivity, independence, and scientific rigor in its educational activities and is committed to protecting learners from promotion, marketing, and commercial bias. All faculty, planner and others in a position to control continuing education content participating in an accredited continuing education activity are required to disclose all financial relationships with ineligible companies. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. The accredited provider is responsible for mitigating all relevant financial relationships in accredited continuing education.  Disclosure of these commitments and/or relationships is included in these activity materials so that participants may formulate their own judgments in interpreting its content and evaluating its recommendations.

This activity may include presentations in which faculty may discuss off-label and/or investigational use of pharmaceuticals or instruments not yet FDA-approved. Participants should note that the use of products outside currently FDA-approved labeling should be considered experimental and are advised to consult current prescribing information for FDA-approved indications.  All materials are included with the permission of the faculty. The opinions expressed are those of the faculty and are not to be construed as those of UNMC.

The accredited provider has mitigated and is disclosing identified relevant financial relationships for the following faculty, planners, and others in control of content prior to assuming their roles.

Faculty Disclosures
All faculty and planning committee members have no conflicts to disclose with the exception of the following:

Faculty 
Christopher Flowers, MD (Moderator)
Professor and Chair, Department of Lymphoma and Myeloma
The University of Texas
MD Anderson Cancer Center
Houston, Texas

Consulting Fees: AbbVie, Bayer,  BeiGene, Celgene Corporation, Denovo Biopharma, Epizyme, Inc., Genentech/Roche, Genmab, Gilead Sciences, Karyopharm Therapeutics, Pharmacyclics/Janssen
Contracted Research & Publishing: 4D, AbbVie, Acerta, Adaptimmune, Allogene, Amgen, Bayer, Celgene Corporation, Cellectis, EMD Serono, Gilead Sciences, Genentech/Roche, Guardant Health

Noopur Raje, MD
Professor of Medicine, Harvard Medical School
Director, Multiple Myeloma Program, Medical Oncology
Massachusetts General Hospital
Boston, Massachusetts

Consulting Fees: Celgene Corporation, Amgen, Janssen, BMS, Bluebird Bio

Planning Committee
The following planning committee members have nothing to disclose:

UNMC: Brenda Ram, CMP, CHCP
Bio Ascend: Patti Bunyasaranand, MS; Lucja Grajkowska, PhD; Dru Dace, PhD; Kraig Steubing

Support
This activity is supported by educational grants from Bristol Myers Squibb and Legend Biotech USA Inc.

Technical Requirements

This activity is best experienced using the most current browser (or one back) of Firefox, Chrome, Safari, Internet Explorer, or Microsoft Edge. For all activities featuring audio you must have a sound card and speakers. To view graphic images and references that appear in separate "pop-up" windows, you must have JavaScript and session cookies enabled on your computer. Adobe Acrobat Reader may be required for certain activities.

Select the Continue button below to begin. You may return later if you are unable to complete the activity at this time.