Experts Debate: Treatment Decisions in Relapsed/Refractory Multiple Myeloma

Date: Friday, December 10, 2021
Time: 11:00 AM - 1:30 PM ET
Live Meeting Location: Georgia World Congress Center - 285 Andrew Young International Blvd NW, Atlanta, GA 30313
Symposium Room: Georgia Ballroom 2, Level 3

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Symposium Overview
This satellite symposium will take place preceding the ASH 2021 Annual Meeting and will be presented by four renowned experts actively engaged in the care of patients with multiple myeloma.

Target Audience
This activity is intended for community and academic medical oncologists, hematologists, advanced practitioners (NP/PA/PharmD), and other clinicians who treat patients with MM and who attend the ASH Annual Meeting.

Learning Objectives
After participating in the activity, participants should be better able to:

Incorporate minimal residual disease assessment when evaluating prognosis and potential relapse
Evaluate treatment approaches for patients with relapsed and/or refractory MM, specifically the decision to include a monoclonal bispecific antibody, or antibody-drug conjugate, CAR T cell therapy, and combination with other agents for triplet therapy
Develop strategies to mitigate treatment-related adverse events that may occur during the care of patients with RR MM
Discuss the results of clinical trials that are investigating emerging novel agents in patients with RR MM

Continuing Education
In support of improving patient care, this activity has been planned and implemented by University of Nebraska Medical Center and Bio Ascend. University of Nebraska Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Nebraska Medical Center designates this live activity for a maximum of 2.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Agenda
11:00 AM Welcome, Introductions, and Presession Survey - Dr. Sagar Lonial

11:10 AM What is the Optimal Partner for CD38 Therapy in First Relapse?
IMID - Dr. Jonathan Kaufman
PI - Dr. Saad Usmani
Panel Discussion and Rebuttals

11:40 AM Is MRD Assessment Useful for Treatment Decisions?
Yes - Dr. Krina Patel
No - Dr. Sagar Lonial
Panel Discussion and Rebuttals

12:10 PM What is the Optimal Class of Agents for Triple Class Refractory MM?
Immunotherapy - Dr. Sagar Lonial
Small Molecules - Dr. Saad Usmani
Panel Discussion and Rebuttals

12:40 PM What is the Optimal Immunotherapy for Targeting BCMA?
CAR T-Cells - Dr. Krina Patel
Bispecific Antibodies/ADCs - Dr. Jonathan Kaufman
Panel Discussion and Rebuttals

1:10 PM Audience Q&A with the Clinical Experts - Moderated by Dr. Sagar Lonial

1:20 PM Recap of Key Points and Post-Session Survey - Dr. Sagar Lonial

1:30 PM Conclusion

Chair
Sagar Lonial, MD, FACP
Chief Medical Officer
Professor and Chair, Department of Hematology and Medical Oncology
Anne and Bernard Gray Family Chair in Cancer
Winship Cancer Institute of Emory University
Atlanta, Georgia

Faculty
Jonathan Kaufman, MD
Professor, Department of Hematology and Medical Oncology
Winship Cancer Institute of Emory University
Atlanta, Georgia

Krina Patel, MD
Associate Professor, Department of Lymphoma/Myeloma
The University of Texas MD Anderson Cancer Center
Houston, Texas

Saad Usmani, MD, MBA, FACP
Chief of Myeloma Service
Memorial Sloan Kettering Cancer Center
New York, New York

Disclosure Information

As a jointly accredited provider, the University of Nebraska Medical Center (UNMC) ensures accuracy, balance, objectivity, independence, and scientific rigor in its educational activities and is committed to protecting learners from promotion, marketing, and commercial bias. Faculty (authors, presenters, speakers) are encouraged to provide a balanced view of therapeutic options by utilizing either generic names or other options available when utilizing trade names to ensure impartiality.

All faculty, planners, and others in a position to control continuing education content participating in a UNMC accredited activity are required to disclose all financial relationships with ineligible companies. As defined by the Standards for Integrity and Independence in Accredited Continuing Education, ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. The accredited provider is responsible for mitigating relevant financial relationships in accredited continuing education. Disclosure of these commitments and/or relationships is included in these activity materials so that participants may formulate their own judgments in interpreting its content and evaluating its recommendations.

This activity may include presentations in which faculty may discuss off-label and/or investigational use of pharmaceuticals or instruments not yet FDA-approved. Participants should note that the use of products outside currently FDA-approved labeling should be considered experimental and are advised to consult current prescribing information for FDA-approved indications.

All materials are included with the permission of the faculty. The opinions expressed are those of the faculty and are not to be construed as those of UNMC.

The accredited provider has mitigated and is disclosing identified relevant financial relationships for the following faculty, planners, and others in control of content prior to assuming their roles:  

Faculty
Sagar Lonial, MD, FACP
Consulting Fees: Amgen Inc., Bristol-Myers Squibb Company, Bluebird, Celgene Corporation, Genentech, Novartis, Sanofi, Takeda Oncology
Other: Board of Directors TG Therapeutics with stock

Jonathan Kaufman, MD
Consulting Fees: Abbvie, Genentech/Roche, Bristol-Myers Squibb Company, Incyte
Contracted Research: Abbvie, Genentech/Roche, Bristol-Myers Squibb Company, Novartis, Heidelberg Pharma, Fortis Therapeutics, Sutro, Janssen, Bluebird

Krina Patel, MD
Consulting Fees: Bristol Myers Squibb Company, Janssen, Pfizer, Arcellx

Saad Usmani, MD, MBA, FACP
Consulting Fees: Amgen, Bristol-Myers Squibb Company, Celgene Corporation, EdoPharma, GSK, Janssen, Sanofi, Seattle Genetics, SecuraBio, SkylineDX, Takeda, TeneoBio
Research Funding: Amgen, Array Biopharma, Bristol-Myers Squibb Company, Celgene Corporation, GSK, Janssen, Merck, Pharmacyclics, Sanofi, Seattle Genetics, SkylineDX, Takeda

Planning Committee
The following planning committee members have nothing to disclose:
UNMC: Brenda Ram, CMP, CHCP
Bio Ascend: Jennifer Bechan, CMP, HMCC; Dru Dace, PhD; Kraig Steubing

Support
This activity is supported by educational grants from Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC, Legend Biotech, Oncopeptides, Inc., and Sanofi Genzyme

Friday Satellite Symposium on Multiple Myeloma, preceding the 63rd ASH Annual Meeting and Exposition.

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